CREATED BIOCOMPATIBLE MICROROBOTS FOR PRECISE DRUG DELIVERY

Scientists at Columbia school of engineering and applied Sciences have created biocompatible microrobots, which can be safely implanted in the human body and control their movements.

A team of scientists under the leadership of Professor Sam Sailly have developed a “locking mechanism” to precisely control the movement and actuation of the moving elements of robots, taking advantage of the unique properties of hydrogels and providing them next to the diffusion and mechanical properties.

Microrobots that do not require a constant source of energy, successfully tested on a model of bone cancer, highlighting within 10 days of doxorubicin, a drug used against malignant tumors. Tumor growth was limited, this was recorded a lower toxicity of chemotherapy, only 1/10 of the standard dose.

To create microrobots Professor saya used the development of the Institute of datalogi, iMEMS platform, which allows development of biocompatible implants with wider spectrum of action and the possibility of wireless control. With its help, the team of scientists were able to combine complex medical devices with biomaterials and to apply their achievements to deliver drugs to desired parts of the body.
Most current flowsin Microdevices have limited biocompatibility because they require batteries or other toxic electronics. Usually, they also lack moving elements. Eight years, the team of Professor Sailly worked on a solution to this problem, based on its technology hydrogels, carefully matched to the rigidity of the structures and modified them to mechanical and diffusion properties so that the robot can move in the right direction, without causing harm to internal organs, and deliver drugs to target. Accurate control was maintained using magnetic forces.

System iMEMS, which was used by scientists at Columbia school, will allow to approach the creation of tiny robots that can safely interact with humans and other living organisms, writes InternetMedicine.

Bradley Nelson, winner of the Guinness prize for “the most advanced of minirobota for medical purposes”, has developed a miniature bio-robots for non-invasive and selective treatment. Genetic modified cells with a cargo of drugs are activated by impulses of the brain and precisely attack the selected target, reducing unwanted side effects.

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